A man and woman have died after their high-powered Lamborghini lost control on a Queensland highway in what has been described as a tragic weekend on the state’s roads.

The fatal crash occurred at 5.40pm on Sunday on the Mount Lindsay Hwy near Beaudesert in the Scenic Rim region.

Police say a 45-year-old woman and 44-year-old man were travelling in a yellow Lamborghini Gallardo when the driver lost control of the luxury sports car.

Both occupants died at the scene.

Witnesses have told police the vehicle was speeding prior to the crash, which has now become a major focus of the investigation.

The yellow Lamborghini Gallardo sustained severe damage in the crash.The yellow Lamborghini Gallardo sustained severe damage in the crash. Credit: 7NEWS Police at the scene.Police at the scene. Credit: 7NEWS

Vision from the crash site shows the once-pristine luxury vehicle reduced to mangled metal.

The tragedy comes after another serious crash in the same region earlier on Sunday morning.

At 10.40am, emergency services responded to a crash at Mount Tambourine where five people were taken to hospital in critical conditions.

Police investigations into both incidents are ongoing.