Police are seeking to speak with a 47-year-old man in connection with the suspected abduction of a young girl in the Northern Territory.

The five-year-old, referred to as Sharon by police, was reported missing about 1.30 am yesterday from Alice Springs.

Officers resumed foot searches for her today, and wish to speak with the man, whose name is Jefferson Lewis.

Police hold fears for missing five-year-old Sharon who disappeared from her Alice Springs home. (NT Police)© Supplied

Police say Sharon was last seen by family when she was put to bed at her home on Marshall Court in Old Timers Camp about 11.30 pm on Saturday.

“Police have conducted an initial search of the area utilising extensive resources and have been unable to locate Sharon,” a statement by NT Police said.

“She was last seen wearing a dark blue short-sleeve T-shirt with a white ring stripe around the neck and a white ring stripe around the end of the sleeves, and a pair of black boxer-style underwear.

“Police are seeking public help to find 47-year-old male, Mr Jefferson Lewis, who police believe can assist with enquiries.”

In a press conference, Acting Commander Mark Grieve said police had been unable to locate Lewis.

“He is believed to have been in the area around that time and staying at the residence,” he said,” Acting Commander Grieve said.

“He currently remains one of the few people who were in Old Timers camp at the time and who has not made themselves known to police, nor have police been able to locate him.

“We do believe Sharon has been abducted.”

Anyone with information should call 131 444.